PD184352 (CI-1040) chemical structure

PD184352 (CI-1040)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1020-5mg

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PD184352 (CI-1040) chemical structure

PD184352 (CI-1040)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
212631-79-3
Formula
C17H14ClF2IN2O2
Small target
MEK
Smiles
C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
Storage conditions
2 years -80 in solvent
Scientific background
PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis.
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