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Dasatinib chemical structure

Dasatinib

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
302962-49-8
Formula
C22H26ClN7O2S
Small target
Bcr-Abl
Smiles
CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO
Storage conditions
2 years -80 in solvent
Synonyms
BMS-354825
Scientific background
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
Technical documents

Documents

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