Imatinib Mesylate chemical structure

Imatinib Mesylate

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1026-250mg

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Imatinib Mesylate chemical structure

Imatinib Mesylate

$208.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
220127-57-1
Formula
C29H31N7O.CH4SO3
Small target
Bcr-Abl
Smiles
CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
Storage conditions
2 years -80 in solvent
Synonyms
CGP-57148B,STI571
Scientific background
Imatinib Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy.
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