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Nilotinib chemical structure

Nilotinib

Regular price $110.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
641571-10-0
Formula
C28H22F3N7O
Small target
Bcr-Abl
Smiles
CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Storage conditions
2 years -80 in solvent
Synonyms
AMN-107
Scientific background
Nilotinib is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
Technical documents

Documents

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