Pazopanib HCl chemical structure

Pazopanib HCl

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1035-10mg

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Pazopanib HCl chemical structure

Pazopanib HCl

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
635702-64-6
Formula
C21H23N7O2S.HCl
Small target
c-Kit
Smiles
CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Storage conditions
2 years -80 in solvent
Synonyms
GW786034 HCl
Scientific background
Pazopanib HCl is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.
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