Tandutinib (MLN518) chemical structure

Tandutinib (MLN518)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1043-25mg

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Tandutinib (MLN518) chemical structure

Tandutinib (MLN518)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
387867-13-2
Formula
C31H42N6O4
Small target
FLT3
Smiles
CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5
Storage conditions
2 years -80 in solvent
Synonyms
CT 53518, NSC726292, MLN518
Scientific background
Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.
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