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SL-327 chemical structure

SL-327

Regular price $203.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
305350-87-2
Formula
C16H12F3N3S
Small target
MEK
Smiles
C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
Storage conditions
2 years -80 in solvent
Scientific background
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII;capable of transport through the blood-brain barrier.
Technical documents

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