Linsitinib (OSI-906) chemical structure

Linsitinib (OSI-906)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1091-5mg

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For research use only — not intended for clinical or diagnostic purposes.
Linsitinib (OSI-906) chemical structure

Linsitinib (OSI-906)

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
867160-71-2
Formula
C26H23N5O
Small target
IGF-1R
Smiles
CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Storage conditions
2 years -80 in solvent
Scientific background
Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
Technical documents

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