PF-04217903 chemical structure

PF-04217903

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1094-5mg

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For research use only — not intended for clinical or diagnostic purposes.
PF-04217903 chemical structure

PF-04217903

$83.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
956905-27-4
Formula
C19H16N8O
Small target
c-Met
Smiles
C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1
Storage conditions
2 years -80 in solvent
Scientific background
PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant). Phase 1.
Technical documents

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