Quisinostat (JNJ-26481585) 2HCl chemical structure

Quisinostat (JNJ-26481585) 2HCl

Vendor: Selleckchem

Type: DNA Damage/DNA Repair

SKU: S1096-5mg

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$158.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Quisinostat (JNJ-26481585) 2HCl chemical structure

Quisinostat (JNJ-26481585) 2HCl

$158.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
DNA Damage/DNA Repair
Cas number
875320-31-3
Formula
C21H28Cl2N6O2
Small target
HDAC
Smiles
CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO.Cl.Cl
Storage conditions
2 years -80 in solvent
Scientific background
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
Technical documents

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