Quisinostat (JNJ-26481585) 2HCl

Name: Quisinostat (JNJ-26481585) 2HCl
Brand: Selleckchem
Price: 158.0 USD
Availability: InStock

Vendor: Selleckchem

Type: DNA Damage/DNA Repair

SKU: S1096-5mg

$158.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

DNA Damage/DNA Repair

Cas number

875320-31-3

Formula

C21H28Cl2N6O2

Small target

HDAC

Smiles

CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO.Cl.Cl

Storage conditions

2 years -80 in solvent

Background

Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.

Quisinostat (JNJ-26481585) 2HCl

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Product Overview

Background

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