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Vatalanib (PTK787) 2HCl chemical structure

Vatalanib (PTK787) 2HCl

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
212141-51-0
Formula
C20H15ClN4.2HCl
Small target
VEGFR
Smiles
C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl
Storage conditions
2 years -80 in solvent
Synonyms
ZK 222584 (cpg-79787) 2HCl
Scientific background
Vatalanib 2HCl (PTK787, ZK 222584, cpg-79787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 3.
Technical documents

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