TAE684 (NVP-TAE684) chemical structure

TAE684 (NVP-TAE684)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1108-5mg

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For research use only — not intended for clinical or diagnostic purposes.
TAE684 (NVP-TAE684) chemical structure

TAE684 (NVP-TAE684)

$120.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
761439-42-3
Formula
C30H40ClN7O3S
Small target
ALK
Smiles
CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Storage conditions
2 years -80 in solvent
Scientific background
TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor which blocked the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM, 100-fold more sensitive for ALK than InsR. TAE684 (NVP-TAE684) induces cell cycle arrest and apoptosis.
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