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Palbociclib (PD-0332991) HCl chemical structure

Palbociclib (PD-0332991) HCl

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
827022-32-2
Formula
C24H29N7O2.HCl
Small target
CDK
Smiles
CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl
Storage conditions
2 years -80 in solvent
Scientific background
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
Technical documents

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