XL147 analogue chemical structure

XL147 analogue

Vendor: Selleckchem

Type: PI3K/Akt/mTOR

SKU: S1118-10mg

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For research use only — not intended for clinical or diagnostic purposes.
XL147 analogue chemical structure

XL147 analogue

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
PI3K/Akt/mTOR
Cas number
956958-53-5
Formula
C21H16N6O2S2
Small target
PI3K
Smiles
CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4
Storage conditions
2 years -80 in solvent
Synonyms
SAR245408
Scientific background
XL147 analogue (SAR245408) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. XL147 analogue induces apoptosis. Phase 1/2.
Technical documents

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