BMS-754807 chemical structure

BMS-754807

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1124-5mg

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For research use only — not intended for clinical or diagnostic purposes.
BMS-754807 chemical structure

BMS-754807

$135.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1001350-96-4
Formula
C23H24FN9O
Small target
c-Met
Smiles
CC1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
Storage conditions
2 years -80 in solvent
Scientific background
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
Technical documents

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