SNS-032 (BMS-387032) chemical structure

SNS-032 (BMS-387032)

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1145-5mg

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For research use only — not intended for clinical or diagnostic purposes.
SNS-032 (BMS-387032) chemical structure

SNS-032 (BMS-387032)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
345627-80-7
Formula
C17H24N4O2S2
Small target
CDK
Smiles
CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCNCC3
Storage conditions
2 years -80 in solvent
Scientific background
SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis.
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