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MK-8245 chemical structure

MK-8245

Regular price $203.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
1030612-90-8
Formula
C17H16BrFN6O4
Small target
SCD
Smiles
C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O
Storage conditions
2 years -80 in solvent
Scientific background
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2.
Technical documents

Documents

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