PD98059 chemical structure

PD98059

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1177-10mg

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PD98059 chemical structure

PD98059

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
167869-21-8
Formula
C16H13NO3
Small target
MEK
Smiles
COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2
Storage conditions
2 years -80 in solvent
Scientific background
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist.
Technical documents

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