CUDC-101 chemical structure

CUDC-101

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1194-1g

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For research use only — not intended for clinical or diagnostic purposes.
CUDC-101 chemical structure

CUDC-101

$2,243.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1012054-59-9
Formula
C24H26N4O4
Small target
EGFR
Smiles
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO
Storage conditions
2 years -80 in solvent
Scientific background
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
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