Tivozanib chemical structure

Tivozanib

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1207-50mg

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Tivozanib chemical structure

Tivozanib

$428.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
475108-18-0
Formula
C22H19ClN4O5
Small target
c-Kit
Smiles
CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
Storage conditions
2 years -80 in solvent
Synonyms
AV-951, KRN-951
Scientific background
Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.
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