Doxorubicin (DOX) HCl

Name: Doxorubicin (DOX) HCl
Brand: Selleckchem
Price: 110.0 USD
Availability: InStock

Vendor: Selleckchem

Type: DNA Damage/DNA Repair

SKU: S1208-10mg

$110.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

DNA Damage/DNA Repair

Cas number

25316-40-9

Formula

C27H29NO11.HCl

Small target

Topoisomerase

Smiles

CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O.Cl

Storage conditions

2 years -80 in solvent

Synonyms

Adriamycin, NSC 123127, Hydroxydaunorubicin HCl

Background

Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease.

Doxorubicin (DOX) HCl

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Product Overview

Background

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