Methotrexate chemical structure

Methotrexate

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1210-100mg

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Methotrexate chemical structure

Methotrexate

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
59-05-2
Formula
C20H22N8O5
Small target
DHFR
Smiles
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Storage conditions
3 years -20°C(in the dark) powder1 year -80°C(in the dark) in solvent
Synonyms
NCI-C04671, Amethopterin, CL14377, WR19039
Scientific background
Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.
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