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Carboplatin chemical structure

Carboplatin

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
41575-94-4
Formula
C6H12N2O4Pt
Small target
DNA/RNA Synthesis
Smiles
C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]
Storage conditions
2 years -80 in solvent
Synonyms
NSC 241240, JM-8, CBDCA
Scientific background
Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
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