OSI-930 chemical structure

OSI-930

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1220-5mg

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For research use only — not intended for clinical or diagnostic purposes.
OSI-930 chemical structure

OSI-930

$113.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
728033-96-3
Formula
C22H16F3N3O2S
Small target
c-Kit
Smiles
C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
Storage conditions
2 years -80 in solvent
Scientific background
OSI-930 is a potent inhibitor of Kit (c-Kit), KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
Technical documents

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