TMZ(Temozolomide) chemical structure

TMZ(Temozolomide)

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1237-25mg

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TMZ(Temozolomide) chemical structure

TMZ(Temozolomide)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
85622-93-1
Formula
C6H6N6O2
Small target
DNA/RNA Synthesis
Smiles
CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
Storage conditions
（in dark and seal）
Synonyms
NSC 362856,CCRG 81045,Methazolastone
Scientific background
TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.
Technical documents

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