TMZ(Temozolomide)

Name: TMZ(Temozolomide)
Brand: Selleckchem
Price: 110.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1237-25mg

$110.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Cell Cycle

Cas number

85622-93-1

Formula

C6H6N6O2

Small target

DNA/RNA Synthesis

Smiles

CN1C(=O)N2C=NC(=C2N=N1)C(=O)N

Storage conditions

（in dark and seal）

Synonyms

NSC 362856,CCRG 81045,Methazolastone

Background

TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.

TMZ(Temozolomide)

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Product Overview

Background

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