JNJ-7706621 chemical structure

JNJ-7706621

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1249-5mg

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$278.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
JNJ-7706621 chemical structure

JNJ-7706621

$278.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
443797-96-4
Formula
C15H12F2N6O3S
Small target
Aurora Kinase
Smiles
C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
Storage conditions
2 years -80 in solvent
Scientific background
JNJ-7706621 is a pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1.
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