PD173074 chemical structure

PD173074

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1264-5mg

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PD173074 chemical structure

PD173074

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
219580-11-7
Formula
C28H41N7O3
Small target
FGFR
Smiles
CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
Storage conditions
2 years -80 in solvent
Scientific background
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells.
Technical documents

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