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XL228 chemical structure

XL228

Regular price $125.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
898280-07-4
Formula
C22H31N9O
Small target
Bcr-Abl
Smiles
CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)N3CCN(C)CC3)NC4=N[NH]C(=C4)C5CC5
Storage conditions
3 years -20°C powder
Scientific background
XL228 is a protein kinase inhibitor with IC50 of 5 nM, 1.4 nM, 3.1 nM, 1.6 nM, 6.1 nM and 2 nM for wild-type ABL kinase, ABL T315I, Aurora A, IGF-1R, SRC and LYN, respectively.
Technical documents

Documents

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