Bafetinib chemical structure

Bafetinib

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1369-5mg

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Bafetinib chemical structure

Bafetinib

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
859212-16-1
Formula
C30H31F3N8O
Small target
Bcr-Abl
Smiles
CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CCC(C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5
Storage conditions
2 years -80 in solvent
Synonyms
INNO-406, NS-187
Scientific background
Bafetinib is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM/19 nM in cell-free assays, does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit.
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