TCS7010 (Aurora A Inhibitor I)

Name: TCS7010 (Aurora A Inhibitor I)
Brand: Selleckchem
Price: 503.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1451-50mg

$503.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Cell Cycle

Cas number

1158838-45-9

Formula

C31H31ClFN7O2

Small target

Aurora Kinase

Smiles

CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F

Storage conditions

2 years -80 in solvent

Synonyms

TC-S 7010

Background

TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.

TCS7010 (Aurora A Inhibitor I)

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Product Overview

Background

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