PHA-680632 chemical structure

PHA-680632

Vendor: Selleckchem

Type: Cell Cycle

SKU: S1454-5mg

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For research use only — not intended for clinical or diagnostic purposes.
PHA-680632 chemical structure

PHA-680632

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
398493-79-3
Formula
C28H35N7O2
Small target
Aurora Kinase
Smiles
CCC1=C(C(=CC=C1)CC)NC(=O)N2CC3=C(C2)NN=C3NC(=O)C4=CC=C(C=C4)N5CCN(CC5)C
Storage conditions
2 years -80 in solvent
Scientific background
PHA-680632 is a potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Technical documents

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