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Pimasertib (AS-703026) chemical structure

Pimasertib (AS-703026)

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1236699-92-5
Formula
C15H15FIN3O3
Small target
MEK
Smiles
C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NCC(CO)O
Storage conditions
2 years -80 in solvent
Synonyms
MSC1936369B, SAR 245509
Scientific background
Pimasertib (AS-703026, MSC1936369B, SAR 245509) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.
Technical documents

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