AEE788 (NVP-AEE788) chemical structure

AEE788 (NVP-AEE788)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1486-5mg

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For research use only — not intended for clinical or diagnostic purposes.
AEE788 (NVP-AEE788) chemical structure

AEE788 (NVP-AEE788)

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
497839-62-0
Formula
C27H32N6
Small target
EGFR
Smiles
CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5
Storage conditions
2 years -80 in solvent
Scientific background
AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2.
Technical documents

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