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Fludarabine chemical structure

Fludarabine

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
21679-14-1
Formula
C10H12FN5O4
Small target
DNA/RNA Synthesis
Smiles
C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N
Storage conditions
2 years -80 in solvent
Synonyms
FaraA, Fludarabinum, NSC 118218
Scientific background
Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.
Technical documents

Documents

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