BIX 02189 chemical structure

BIX 02189

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1531-5mg

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BIX 02189 chemical structure

BIX 02189

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1094614-85-3
Formula
C27H28N4O2
Small target
MEK
Smiles
CN(C)CC1=CC(=CC=C1)N=C(C2=CC=CC=C2)C3=C(NC4=C3C=CC(=C4)C(=O)N(C)C)O
Storage conditions
2 years -80 in solvent
Scientific background
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
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