Pomalidomide chemical structure

Pomalidomide

Vendor: Selleckchem

Type: Apoptosis

SKU: S1567-50mg

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Pomalidomide chemical structure

Pomalidomide

$143.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
19171-19-8
Formula
C13H11N3O4
Small target
TNF-alpha
Smiles
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Storage conditions
2 years -80 in solvent
Synonyms
CC-4047
Scientific background
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.
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