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PD318088 chemical structure

PD318088

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
391210-00-7
Formula
C16H13BrF3IN2O4
Small target
MEK
Smiles
C1=CC(=C(C=C1I)F)NC2=C(C(=C(C=C2C(=O)NOCC(CO)O)Br)F)F
Storage conditions
2 years -80 in solvent
Scientific background
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
Technical documents

Documents

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