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Deferasirox chemical structure

Deferasirox

Regular price $110.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
201530-41-8
Formula
C21H15N3O4
Small target
P450 (e.g. CYP17)
Smiles
C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O
Storage conditions
2 years -80 in solvent
Synonyms
CGP-72670, ICL-670
Scientific background
Deferasirox is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.
Technical documents

Documents

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