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Simvastatin chemical structure

Simvastatin

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
79902-63-9
Formula
C25H38O5
Small target
HMG-CoA Reductase
Smiles
CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
Storage conditions
2 years -80 in solvent
Synonyms
MK 733
Scientific background
Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.
Technical documents

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