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PCI-34051 chemical structure

PCI-34051

Regular price $128.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
DNA Damage/DNA Repair
Cas number
950762-95-5
Formula
C17H16N2O3
Small target
HDAC
Smiles
COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
Storage conditions
2 years -80 in solvent
Scientific background
PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis.
Technical documents

Documents

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