PF-573228 chemical structure

PF-573228

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2013-10mg

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PF-573228 chemical structure

PF-573228

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
869288-64-2
Formula
C22H20F3N5O3S
Small target
FAK
Smiles
CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
Storage conditions
2 years -80 in solvent
Scientific background
PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.
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