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Roflumilast chemical structure

Roflumilast

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
162401-32-3
Formula
C17H14Cl2F2N2O3
Small target
PDE
Smiles
C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
Storage conditions
2 years -80 in solvent
Synonyms
APTA 2217, B9302-107, BY 217, BYK 20869
Scientific background
Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.
Technical documents

Documents

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