Infigratinib (BGJ398) chemical structure

Infigratinib (BGJ398)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2183-5mg

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Infigratinib (BGJ398) chemical structure

Infigratinib (BGJ398)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
872511-34-7
Formula
C26H31Cl2N7O3
Small target
FGFR
Smiles
CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
Storage conditions
2 years -80 in solvent
Synonyms
NVP-BGJ398
Scientific background
Infigratinib (BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.
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