Allitinib tosylate chemical structure

Allitinib tosylate

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2185-5mg

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Allitinib tosylate chemical structure

Allitinib tosylate

$203.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1050500-29-2
Formula
C24H18ClFN4O2,C7H8O3S
Small target
EGFR
Smiles
CC1=CC=C(C=C1)S(=O)(=O)O.C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
Storage conditions
2 years -80 in solvent
Synonyms
AST-1306 TsOH, AST-6
Scientific background
Allitinib tosylate (AST-1306 TsOH, AST-6) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases.
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