R406 chemical structure

R406

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2194-5mg

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For research use only — not intended for clinical or diagnostic purposes.
R406 chemical structure

R406

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
841290-81-1
Formula
C22H23FN6O5.C6H6O3S
Small target
FLT3
Smiles
CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
Storage conditions
2 years -80 in solvent
Synonyms
R406 besylate
Scientific background
R406(R406 besylate) is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1.
Technical documents

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