BMS-794833 chemical structure

BMS-794833

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2201-5mg

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For research use only — not intended for clinical or diagnostic purposes.
BMS-794833 chemical structure

BMS-794833

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1174046-72-0
Formula
C23H15ClF2N4O3
Small target
c-Met
Smiles
C1=CC(=CC=C1C2=CNC=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)F
Storage conditions
2 years -80 in solvent
Scientific background
BMS-794833 is a potent ATP competitive inhibitor of Met (c-Met)/VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.
Technical documents

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