NVP-BHG712 chemical structure

NVP-BHG712

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2202-5mg

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For research use only — not intended for clinical or diagnostic purposes.
NVP-BHG712 chemical structure

NVP-BHG712

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
940310-85-0
Formula
C26H20F3N7O
Small target
Bcr-Abl
Smiles
CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=C4C=NN(C4=NC(=N3)C5=CN=CC=C5)C
Storage conditions
2 years -80 in solvent
Scientific background
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Technical documents

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