Fostamatinib (R788) disodium chemical structure

Fostamatinib (R788) disodium

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2206-1g

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Fostamatinib (R788) disodium chemical structure

Fostamatinib (R788) disodium

$2,993.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1025687-58-4
Formula
C23H24FN6O9P.2Na
Small target
Syk
Smiles
CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.[Na+].[Na+]
Storage conditions
2 years -80 in solvent
Synonyms
Tamatinib Fosdium
Scientific background
Fostamatinib disodium (R788, Tamatinib Fosdium), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
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