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Irinotecan HCl Trihydrate chemical structure

Irinotecan HCl Trihydrate

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
DNA Damage/DNA Repair
Cas number
136572-09-3
Formula
C33H38N4O6.HCl.3H2O
Small target
Topoisomerase
Smiles
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl
Storage conditions
2 years -80 in solvent
Synonyms
CPT-11 HCl Trihydrate
Scientific background
Irinotecan HCl Trihydrate is a hydrochloride trihydrate of irinotecan (Camptosar, Campto, CPT-11) which is a topoisomerase I inhibitor with IC50 of 15.8 and 5.17 μM for LoVo cells and HT-29 cells, respectively.
Technical documents

Documents

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