Apatinib (YN968D1) mesylate chemical structure

Apatinib (YN968D1) mesylate

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2221-10mg

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Apatinib (YN968D1) mesylate chemical structure

Apatinib (YN968D1) mesylate

$240.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1218779-75-9
Formula
C25H27N5O4S
Small target
VEGFR
Smiles
C[S](O)(=O)=O.O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=CC=CN=C3NCC4=CC=NC=C4
Storage conditions
2 years -80 in solvent
Synonyms
YN968D1, Rivoceranib
Scientific background
Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.
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